TY - CHAP M1 - Book, Section TI - Chapter 20. Acute Liver Failure: How to Orchestrating Emergency Critical Care Interventions A1 - Kalb, Thomas H. A1 - Frontera, Jennifer A. A2 - Farcy, David A. A2 - Chiu, William C. A2 - Flaxman, Alex A2 - Marshall, John P. PY - 2012 T2 - Critical Care Emergency Medicine AB - A patient who presents emergently with acute liver failure (ALF) has an overall greater likelihood of either dying or requiring emergent transplantation than recovering without transplant.1 Regardless of etiology, the unifying feature of ALF is a compact clinical timeline and a rapid, often precipitous natural history of disease. Whereas spontaneous recovery of liver function is possible with supportive measures, particularly with acetaminophen overdose, there remains a significant risk of spiraling decline after presentation with multiorgan failure, bleeding, and infectious complications often heralded by high-grade encephalopathy with cerebral edema.2 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=55812328 ER -