TY - CHAP M1 - Book, Section TI - Antidotes in Depth A1 - Hoffman, Robert S. A1 - Nelson, Lewis S. A1 - Howland, Mary Ann A2 - Hoffman, Robert S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Nelson, Lewis S. A2 - Goldfrank, Lewis R. PY - 2015 T2 - Goldfrank's Toxicologic Emergencies, 10e AB - Benzodiazepines are used as first-line anticonvulsants for virtually all xenobiotic induced seizures; as sedatives of choice for most forms of xenobiotic induced agitation; as muscle relaxants for diverse disorders such as serotonin toxicity, neuroleptic malignant syndrome, and poisoning from strychnine or black widow spider envenomation; and as ­sedatives for withdrawal from ethanol, γ-hydroxybutyric acid, and other ­sedatives. Additional distinct indications for benzodiazepines can be found in overdose from chloroquine and possibly other quinine derived antimalarials, and in patients with cocaine associated myocardial ischemia and infarction. This Antidotes in Depth provides a summary of the clinical pharmacology of benzodiazepines in order to provide the reader with the background necessary to administer these drugs as safely and effectively as possible. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1108422446 ER -