TY - CHAP M1 - Book, Section TI - Antidotes in Depth A1 - Howland, Mary Ann A2 - Hoffman, Robert S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Nelson, Lewis S. A2 - Goldfrank, Lewis R. PY - 2015 T2 - Goldfrank's Toxicologic Emergencies, 10e AB - Silibinin is the active ingredient in milk thistle, Silybum marianum, purported to prevent and treat amatoxin induced liver failure. Legalon SIL is a purified silibinin derivative available via an FDA approved open treatment as an investigational new drug (IND) for IV administration in patients suspected of ingesting amatoxin containing mushrooms. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1108423074 ER -