TY - CHAP M1 - Book, Section TI - Antibacterials, Antifungals, and Antivirals A1 - Stork, Christine M. A2 - Hoffman, Robert S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Nelson, Lewis S. A2 - Goldfrank, Lewis R. PY - 2015 T2 - Goldfrank's Toxicologic Emergencies, 10e AB - Antimicrobials, including antibacterials, antifungals, and antivirals, have significantly improved the clinical care of infected patients since the introduction of penicillin in the 1940s. The development of antimicrobial-resistant strains of these pathogens has continually expanded the number of antimicrobials necessary, and this has increased the overall potential for toxicity after use. Fortunately, toxicity due to acute overdose is limited and chronic therapeutic doses are safe in the majority of patients. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1108430271 ER -