TY - CHAP M1 - Book, Section TI - Ethanol Withdrawal A1 - Gold, Jeffrey A. A1 - Nelson, Lewis S. A2 - Hoffman, Robert S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Nelson, Lewis S. A2 - Goldfrank, Lewis R. PY - 2015 T2 - Goldfrank's Toxicologic Emergencies, 10e AB - The medical problems associated with alcoholism and alcohol withdrawal were initially described by Pliny the Elder in the first century B.C. In his work Naturalis Historia, the alcoholic and alcohol withdrawal were described as follows: “…drunkenness brings pallor and sagging cheeks, sore eyes, and trembling hands that spill a full cup, of which the immediate punishment is a haunted sleep and unrestful nights. …”54 Initial treatments as described by Osler at the turn of the 20th century were focused on supportive care, including confinement to bed, cold baths to reduce fever, and judicious use of potassium bromide, chloral hydrate, hyoscine, and, possibly, opium.20 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1108432874 ER -