TY - CHAP M1 - Book, Section TI - Organophosphates and Carbamates A1 - Gussow, Leon A2 - Schafermeyer, Robert A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. PY - 2014 T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 4e AB - Organophosphate and carbamate insecticides inactivate the enzyme acetylcholinesterase resulting in a cholinergic crisis with the immediate threat to life being respiratory failure.The diagnosis is clinical with the history of exposure being key; the combination of miosis and increased salivation is relatively specific.Immediate administration of very large doses of atropine is life saving.Pralidoxime is an adjunctive antidote for organophosphate but not for carbamate poisoning. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessemergencymedicine.mhmedical.com/content.aspx?aid=1105687222 ER -