RT Book, Section A1 Shaffer, Robert W. A1 Santen, Sally A. A2 Tintinalli, Judith E. A2 Stapczynski, J. Stephan A2 Ma, O. John A2 Yealy, Donald M. A2 Meckler, Garth D. A2 Cline, David M. SR Print(0) ID 1121500653 T1 Acquired Bleeding Disorders T2 Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071794763 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1121500653 RD 2024/04/20 AB Normal regulation of bleeding is a complex process involving platelets and the coagulation system (see chapter 232, "Tests of Hemostasis"). Platelet defects typically manifest with petechiae and mucosal bleeding, whereas coagulation defects usually present as spontaneous or excessive hemorrhage. Management of significant acquired bleeding disorders should be discussed with a hematologist because there are often subtleties in diagnosis and treatment.