RT Book, Section
A1 Franco, Alexandra
A1 Mazuski, John E.
A1 Eaton, Stephen R.
A1 Husain, Kareem D.
A1 Tuda, Claudio
A2 Farcy, David A.
A2 Chiu, William C.
A2 Marshall, John P.
A2 Osborn, Tiffany M.
SR Print(0)
ID 1135703150
T1 Clostridium Difficile Infection
T2 Critical Care Emergency Medicine, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071838764
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1135703150
RD 2024/04/18
AB Clostridium  difficile  Infection  (CDI)  is  the  most  common  cause  of  infectious  nosocomial  diarrhea  in  adults  in  developed  countries.  Currently,  it  is  considered  an  important  transmissible  nosocomial  disease  causes  often  appear  in  outbreaks  within  healthcare  facilities.  Prior  to  1977,  the  clostridial  disease  most  commonly  described  was  a  form  of  skin  and  soft-tissue  gangrene  caused  by  a  strain  named  Clostridium  perfringens,  with  fatal  outcomes  often  reported.  Once  the  antibiotic  era  started,  an  antibiotic-associated  colitis  was  first  described  in  animal  models  caused  by  Clostridium  difficile  (C.  difficile).  Shortly  after,  C.  difficile  associated  colitis  became  the  most  common  clostridial  infection  among  humans  in  the  hospital  setting.1–4