RT Book, Section A1 Punja, Mohan A1 Hoffman, Robert J. A2 Farcy, David A. A2 Chiu, William C. A2 Marshall, John P. A2 Osborn, Tiffany M. SR Print(0) ID 1135703218 T1 Approach to Poisoning T2 Critical Care Emergency Medicine, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071838764 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1135703218 RD 2024/10/07 AB Patients with poison exposure and toxicity may present with a spectrum of various clinical signs, symptoms, and problems. Most of these are very straightforward and easily anticipated, but others may be unpredictable or associated with exposure to unidentified substances that hinder the clinician from knowing what to expect. There are, however, general principles that may be employed as a framework on which the approach to most poisonings may be based. These are employed when managing adverse effects from poisoning by known or unidentified substances. Less than 5% of poisonings require use of specific antidotes; thorough general supportive care is the most important approach in caring for most poisoned patients.1