RT Book, Section A1 Hoffman, Robert J. A2 Farcy, David A. A2 Chiu, William C. A2 Marshall, John P. A2 Osborn, Tiffany M. SR Print(0) ID 1135703355 T1 The Critically Ill Poisoned Patient T2 Critical Care Emergency Medicine, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071838764 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1135703355 RD 2024/04/19 AB The 2001 publication by the American Heart Association, TOX-ACLS Toxicologic-Oriented Advanced Life Support,1 marked wide recognition that critical illness resulting from poisoning may require very different management from similar illness occurring in the nonpoisoned patient. That publication made specific suggestions for management of dysrhythmias and other toxicity caused by cocaine, calcium channel blockers and β-blockers, opioids, tricyclic antidepressants, and drug-induced cardiovascular shock. In 2010, the updated American Heart Association ACLS guidelines contained specific evaluation and recommendations regarding poisoning with these same aforementioned toxins, as well as cyanide, digoxin, and antidotal therapy with flumazenil and lipid emulsion.2 The relevance of those publications is recognition that proper management of many clinical problems caused by toxins differs or deviates from management of the same clinical problem occurring in the nonpoisoned patient.