RT Book, Section A1 Kerrigan, Kathleen A2 Cydulka, Rita K. A2 Fitch, Michael T. A2 Joing, Scott A. A2 Wang, Vincent J. A2 Cline, David M. A2 Ma, O. John SR Print(0) ID 1143141224 T1 Emergencies After 20 Weeks of Pregnancy and The Postpartum Period T2 Tintinalli's Emergency Medicine Manual, 8e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071837026 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1143141224 RD 2022/08/16 AB Deep vein thrombosis (DVT) and pulmonary embolism (PE) are the leading causes of maternal morbidity and mortality in industrialized nations. Symptoms are similar to those seen in nonpregnant women. Evaluation for DVT should begin with ultrasound of the lower extremities. If there is a concern for PE initiate the evaluation with a chest radiograph. d-dimer may not be helpful to diagnose or exclude thromboembolic disease as levels increase throughout pregnancy. Consensus guidelines recommend obtaining a V/Q scan or CT pulmonary angiography next if the chest radiograph is nondiagnostic. DVT and PE are treated with unfractionated heparin or low-molecular-weight heparin. Do not use warfarin in pregnancy as it crosses the placenta, potentially causing fetal CNS abnormalities and embryopathies such as bone and cartilage abnormalities as well as nasal and limb hypoplasia.