RT Book, Section
A1 Perina, Debra
A1 Woods, William A.
A2 Tintinalli, Judith E.
A2 Ma, O. John
A2 Yealy, Donald M.
A2 Meckler, Garth D.
A2 Stapczynski, J. Stephan
A2 Cline, David M.
A2 Thomas, Stephen H.
SR Print(0)
ID 1166812122
T1 Ketoacidotic Syndromes
T2 Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260019933
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1166812122
RD 2024/04/25
AB Ketones  form  a  viable  energy  source  used  daily  by  the  body  in  response  to  variations  in  carbohydrate  intake  and  energy  demand.  There  are  several  conditions  that  may  result  in  excessive  production  of  ketoacids  that  can  result  in  a  significant  metabolic  acidosis.  The  challenge  for  the  clinician  is  to  differentiate  states  of  excessive,  uncontrolled  ketoacidosis  from  physiologic  ketonemia,  from  states  where  excessive  ketones  may  be  produced,  or  from  conditions  or  a  toxin  altering  normal  metabolism.1  The  pathophysiology  of  ketoacidosis  is  poorly  understood.  Authors  speculate  about  the  hormonal  milieu  and  pre-existing  glycogen  stores  that,  under  some  circumstances,  will  tip  certain  patients  into  pathologic  ketoacidosis.