RT Book, Section A1 Wathen, Joe E. A1 Wiersma, Alexandria J. A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. A2 Schafermeyer, Robert SR Print(0) ID 1155167817 T1 Procedural Sedation and Analgesia T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 5e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259860751 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1155167817 RD 2024/03/29 AB Continuous monitoring of oxygen saturation and heart rate will identify the most common serious risk of sedation, hypoxia.Combinations of drugs may increase adverse effects of each, such as respiratory depression; consider reducing dosing when combining sedation medications.Avoid ketamine in infants younger than 3 months due to the risk of airway complications.Emergence reactions associated with ketamine appear to be related to the pretreatment anxiety level of the patient.Obesity is an independent risk factor for adverse events. Extra caution should be taken when sedating these patients.