RT Book, Section A1 Kecskes, Susan A. A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. A2 Schafermeyer, Robert SR Print(0) ID 1155427927 T1 Hypo- and Hypernatremia Abnormalities T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 5e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259860751 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1155427927 RD 2024/03/28 AB Sodium concentration reflects both the sodium and water contents of the body.Arginine vasopressin (AVP) is one of the primary regulatory hormones for sodium concentration. It responds to the changes in osmolality and intravascular volume to restore homeostasis to the body.Hypernatremia may result from:Primary sodium excessHypovolemic hypernatremiaHypernatremia should generally be corrected gradually to avoid the complication of cerebral edema.Aggressive treatment of hyponatremia may lead to the osmotic demyelination syndrome.