RT Book, Section A1 Sivilotti, Marco L. A. A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. A2 Schafermeyer, Robert SR Print(0) ID 1155748558 T1 Acetaminophen T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 5e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259860751 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1155748558 RD 2024/03/28 AB Widely available in both prescription and OTC products, acetaminophen is a common pediatric overdose.Acetylcysteine is the antidote for acetaminophen overdose and can be given orally or intravenously.Treatment with acetylcysteine is prone to dosing errors but is rarely indicated in children less than 6 years of age.Acetylcysteine is nearly 100% effective when started within 8 hours of acetaminophen ingestion.A child less than 6 years of age can be safely discharged following an acetaminophen exposure if the maximum ingested dose is less than 200 mg/kg or if acetaminophen is not detected in the serum at least 1 hour after ingestion.