RT Book, Section A1 Lowry, Jennifer A. A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. A2 Schafermeyer, Robert SR Print(0) ID 1155748612 T1 Nonsteroidal Anti-Inflammatory Drugs T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 5e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259860751 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1155748612 RD 2024/04/24 AB Nonsteroidal anti-Inflammatory drugs (NSAIDs) are relatively devoid of toxicity in the overdose setting.Patients who develop toxicity exhibit central nervous system or gastrointestinal signs and symptoms.Overdose of NSAIDs has been associated with an anion-gap acidosis.Long-term use of NSAIDs is associated with nephrotoxicity, including acute tubular necrosis, acute interstitial nephritis, and acute renal failure.