RT Book, Section A1 Gussow, Leon A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. A2 Schafermeyer, Robert SR Print(0) ID 1155749405 T1 Organophosphates and Carbamates T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 5e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259860751 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1155749405 RD 2024/10/07 AB Organophosphate and carbamate insecticides inactivate the enzyme acetylcholinesterase producing a cholinergic crisis, with the immediate threat to life being respiratory failure.The diagnosis of organophosphate or carbamate poisoning is clinical, with the history of exposure being key; the combination of miosis and increased salivation is relatively specific.Immediate administration of adequate doses of atropine can be life-saving.Pralidoxime is an adjunctive antidote for organophosphate but not for carbamate poisoning.