RT Book, Section A1 Swoboda, Henry D. A2 Reichman, Eric F. SR Print(0) ID 1159804311 T1 Subcutaneous Extravasation and Infiltration Management T2 Reichman's Emergency Medicine Procedures, 3e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259861925 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1159804311 RD 2025/02/18 AB Extravasation and infiltration events are common occurrences with intravenous (IV) therapy and diagnostics (Figure 141-1). Some sources cite an incidence of 10% to 30%.1 The incidence of extravasation of specific agents (e.g., intravenous contrast or vasopressors) is low.2,3 Carefully placed IV catheters for chemotherapy have an incidence of extravasation as low as 0.01%.4 Acute chemotherapeutic medication extravasations are infrequently encountered in the Emergency Department. Understanding extravasations and their treatment is important due to the high degree of morbidity, the limited application of antidotes, and the increasing presence of standalone Emergency Departments and infusion centers.5 An understanding of the early recognition and treatment of chemotherapeutic extravasations is increasingly important.6