RT Book, Section
A1 O’Rourke, Kevin
A2 Reichman, Eric F.
SR Print(0)
ID 1159810481
T1 Plantar Wart Management
T2 Reichman's Emergency Medicine Procedures, 3e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259861925
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1159810481
RD 2024/04/19
AB Plantar  warts  (i.e.,  verruca  pedis)  are  caused  by  infection  of  the  epidermal  skin  layer  with  the  human  papillomavirus  (HPV).  Plantar  warts  were  discussed  as  far  back  as  the  ancient  Greeks  and  Romans.  They  were  subsequently  identified  as  being  caused  by  infectious  agents  in  the  late  1800s.  HPV,  a  member  of  the  Papovaviridae  family,  was  identified  in  1949  and  is  composed  of  double-stranded  DNA.  The  peak  incidence  of  plantar  warts  occurs  in  the  teenage  years.1  They  are  estimated  to  occur  in  10%  of  children  and  young  adults,  with  a  greater  prevalence  in  females.  HPV  enters  the  host  keratinocyte  through  an  epidermal  abrasion  with  the  help  of  a  transiently  impaired  immune  system.  It  is  found  in  the  upper  epidermis  and  results  in  squamous  epithelial  cell  hyperplasia.  Numerous  types  of  HPV  exist.  Simple  plantar  warts  are  mainly  due  to  HPV  types  1,  2,  4,  27,  or  57.