RT Book, Section
A1 Roldan, Carlos J.
A1 Mehta, Amit
A2 Reichman, Eric F.
SR Print(0)
ID 1159811132
T1 Autotransfusion
T2 Reichman's Emergency Medicine Procedures, 3e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259861925
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1159811132
RD 2024/04/19
AB Trauma  is  the  leading  cause  of  death  in  children  and  adults  under  44  years  of  age.1  Exsanguination  plays  a  significant  role  in  as  many  as  half  of  these  deaths,  with  hemorrhagic  shock  the  most  common  cause  for  potentially  preventable  death.2  Hemorrhagic  shock  is  a  primary  indication  for  the  transfusion  of  homologous  blood  products.  Transfusions  with  homologous  blood  products  carry  the  possibility  of  associated  complications  including  transfusion  reactions,  transmission  of  infectious  diseases,  and  sensitization  to  antigens.3  Massive  transfusions  are  associated  with  the  additional  complications  of  acidosis,  dilutional  coagulopathy,  and  hypothermia.  Transfusion  of  homologous  blood  products  in  the  trauma  patient  has  been  independently  associated  with  an  increase  in  both  morbidity  and  mortality,  particularly  when  transfusing  older  stored  blood  products.4-6  Blood  centers  have  more  than  doubled  the  prices  of  blood  products  in  recent  years  due  to  a  decline  in  blood  donors,  higher  skilled  labor  costs,  and  increases  in  the  cost  of  testing  and  processing  blood.7  There  is  evidence  that  the  best  replacement  for  whole  blood  loss  may  be  fresh  whole  blood.8