RT Book, Section A1 Nasr, Ned F. A1 Al-Jindi, Piotr C. A1 Nasr, Isam F. A2 Reichman, Eric F. SR Print(0) ID 1159794308 T1 Rapid Sequence Intubation T2 Reichman's Emergency Medicine Procedures, 3e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259861925 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1159794308 RD 2023/09/29 AB Rapid sequence intubation (RSI) of anesthesia is sometimes referred to as a “crash” intubation. The definition of RSI is the near simultaneous administration of a neuromuscular blocking drug and a sedative to induce unconsciousness and paralysis for endotracheal intubation. It has become a safe and effective method of establishing emergent airway control in patients with suspected life-threatening emergencies. It ensures optimal patient compliance in the best possibly controlled environment that can be achieved in the Emergency Department (ED). RSI in its classical description involves preoxygenation followed by the near simultaneous administration of a potent sedative-hypnotic agent and a neuromuscular blocking agent, application of cricoid pressure, avoidance of positive-pressure ventilation by mask, and intubation with a cuffed endotracheal tube.1-21 Various pretreatment drug regimens have been advocated to prevent the potentially deleterious side effects of aspiration of gastric contents, cardiovascular excitation or depression, and intracranial pressure elevation.