RT Book, Section A1 Abramson, Tiffany A1 Desai, Shoma A2 Reichman, Eric F. SR Print(0) ID 1159796990 T1 Intracardiac Injection T2 Reichman's Emergency Medicine Procedures, 3e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259861925 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1159796990 RD 2024/10/04 AB The practice of intracardiac injection originated in the 1800s and had been strongly advocated for years before it began to fall out of favor.1-3 It was commonly performed throughout the 1960s, as it was thought to be the most expeditious route of drug delivery during a cardiac arrest.4,5 By the mid-1970s, the practice of intracardiac injection declined. Safer and simpler routes of medication administration (i.e., intravenous, endotracheal, and intraosseous) became available. Experimental data suggested that there was no advantage to intracardiac injection over intravenous administration of medications.6 Cardiopulmonary resuscitation (CPR) must be interrupted to perform an intracardiac injection. The time required for this procedure may be prolonged in difficult patients or in inexperienced hands. Many serious complications may occur from an intracardiac injection.5 Intracardiac injection should be considered when no other access is readily available.7