RT Book, Section A1 Rao, Rama B. A2 Nelson, Lewis S. A2 Howland, Mary Ann A2 Lewin, Neal A. A2 Smith, Silas W. A2 Goldfrank, Lewis R. A2 Hoffman, Robert S. SR Print(0) ID 1163006246 T1 Intrathecal Administration of Xenobiotics T2 Goldfrank's Toxicologic Emergencies, 11e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259859618 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1163006246 RD 2024/03/28 AB Cerebrospinal fluid (CSF) is produced by the choroid plexus that lines the cerebral ventricles at a rate of 15 to 30 mL/h, or approximately 500 mL/day in adults.57 Cerebrospinal fluid flows in a rostral to caudal direction and is reabsorbed through the arachnoid villi directly into the venous circulation. The estimated total volume of CSF is 130 to 150 mL in healthy adults and 35 mL in infants.57,74,99