RT Book, Section
A1 Smith, Silas W.
A1 Howland, Mary Ann
A2 Nelson, Lewis S.
A2 Howland, Mary Ann
A2 Lewin, Neal A.
A2 Smith, Silas W.
A2 Goldfrank, Lewis R.
A2 Hoffman, Robert S.
SR Print(0)
ID 1163006519
T1 Activated Charcoal
T2 Goldfrank's Toxicologic Emergencies, 11e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259859618
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1163006519
RD 2024/04/19
AB Activated  charcoal  (AC)  is  an  excellent  nonspecific  adsorbent.  Conclusions  regarding  the  role  of  AC  in  poison  management  are  achieved  through  the  integration  of  pharmacologic  data,  controlled  volunteer  trials,  studies  in  heterogeneous  patients  with  overdose  or  poisoning,  and  clinical  experience.  Activated  charcoal  is  provided  to  a  patient  after  a  risk-to-benefit  assessment  of  the  presumed  ingested  xenobiotic  and  patient-specific  factors  and  circumstances.  Benefits  include  preventing  absorption  or  enhancing  elimination  by  blocking  enterohepatic  or  enteroenteric  recirculation  of  a  potentially  toxic  xenobiotic;  risks  include  vomiting  and  subsequent  aspiration  pneumonitis.  A  detailed  discussion  of  the  merits  of  AC  as  a  decontamination  strategy  is  presented  in  Chap.  5.