RT Book, Section
A1 Smith, Silas W.
A1 Howland, Mary Ann
A2 Nelson, Lewis S.
A2 Howland, Mary Ann
A2 Lewin, Neal A.
A2 Smith, Silas W.
A2 Goldfrank, Lewis R.
A2 Hoffman, Robert S.
SR Print(0)
ID 1163006569
T1 Whole-Bowel Irrigation and Other Intestinal Evacuants
T2 Goldfrank's Toxicologic Emergencies, 11e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259859618
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1163006569
RD 2024/04/19
AB One  approach  to  altering  the  pharmacokinetics  of  a  xenobiotic  is  to  administer  a  gastrointestinal  (GI)  evacuant.  Selected  patients  benefit  from  minimizing  systemic  exposure  by  decreasing  GI  transit  time  and  increasing  rectal  evacuation.  The  most  effective  process  of  evacuating  the  GI  tract  in  poisoned  patients  is  referred  to  as  whole-bowel  irrigation  (WBI).  Whole-bowel  irrigation  is  typically  accomplished  using  polyethylene  glycol  with  a  balanced  electrolyte  lavage  solution  (PEG-ELS).  Unless  stated  otherwise,  WBI  will  mean  WBI  with  PEG-ELS.  A  detailed  discussion  of  the  merits  of  WBI  in  the  context  of  various  decontamination  strategies  is  provided  in  Chap.  5.