RT Book, Section
A1 Zuckerman, Matthew D.
A1 Church, Richard J.
A2 Nelson, Lewis S.
A2 Howland, Mary Ann
A2 Lewin, Neal A.
A2 Smith, Silas W.
A2 Goldfrank, Lewis R.
A2 Hoffman, Robert S.
SR Print(0)
ID 1163008263
T1 Gastrointestinal Principles
T2 Goldfrank's Toxicologic Emergencies, 11e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259859618
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1163008263
RD 2024/04/24
AB Humans  are  in  constant  contact  with  xenobiotics.  In  addition  to  its  critical  role  in  absorbing  nutrients,  the  gastrointestinal  (GI)  tract  forms  the  initial  functional  barrier  between  ingested  material  and  the  body.  An  understanding  of  the  structure,  physiology,  and  innervation  of  the  GI  tract  is  critical  to  the  toxicologic  concepts  of  absorption,  motility,  and  toxic  insult.  This  chapter  discusses  the  normal  role  of  the  GI  tract  and  its  relationship  to  toxicology.  Anatomic,  pathologic,  and  microbiologic  principles  are  discussed,  including  the  role  of  the  GI  tract  in  the  metabolism  of  xenobiotics.  Types  of  GI  pathologies  and  their  clinical  manifestations  are  discussed,  with  examples  when  appropriate.