RT Book, Section A1 Takematsu, Mai A1 Chiang, William K. A2 Nelson, Lewis S. A2 Howland, Mary Ann A2 Lewin, Neal A. A2 Smith, Silas W. A2 Goldfrank, Lewis R. A2 Hoffman, Robert S. SR Print(0) ID 1163008991 T1 Otolaryngologic Principles T2 Goldfrank's Toxicologic Emergencies, 11e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259859618 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1163008991 RD 2024/04/23 AB Many xenobiotics adversely affect the senses of olfaction, gustation, and cochlear–vestibular functions. Although these toxic effects are not life-­threatening they are frequently distressful to patients. Furthermore, because of the dearth of access to standardized diagnostic techniques and normal parameters, such adverse effects are sometimes overlooked or dismissed by health care providers, despite significant patient distress and dysfunction. This is particularly true for disorders of olfaction and gustation. This chapter reviews the anatomy and physiology of these senses, describes the effects of xenobiotics on these senses, and examines the significant diagnostic information these senses contribute to identifying the presence of xenobiotics. ­Understanding the effects of xenobiotics on these senses allows for early detection, removal, and prevention of future events. In occupational settings, understanding these principles help prevent permanent and life-threatening injuries.