RT Book, Section
A1 Stork, Christine M.
A2 Nelson, Lewis S.
A2 Howland, Mary Ann
A2 Lewin, Neal A.
A2 Smith, Silas W.
A2 Goldfrank, Lewis R.
A2 Hoffman, Robert S.
SR Print(0)
ID 1163012572
T1 Antibacterials, Antifungals, and Antivirals
T2 Goldfrank's Toxicologic Emergencies, 11e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259859618
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1163012572
RD 2024/04/23
AB The  introduction  of  penicillin  in  the  1940s  revolutionized  the  care  of  patients  with  infectious  diseases.  Antimicrobials,  including  all  categories  of  antibacterials,  antifungals,  and  antivirals,  significantly  improve  the  clinical  care  and  ­outcome  of  infected  patients.  Since  early  in  their  introduction,  the  development  of  antimicrobial-resistant  strains  of  these  pathogens  has  driven  an  increase  in  the  number  of  antimicrobials  necessary.  This,  in  turn,  continues  to  increase  the  overall  potential  for  toxicity  after  use.  Fortunately,  with  most  antimicrobials,  toxicity  due  to  acute  overdose  is  limited  and  chronic  therapeutic  doses  are  safe.