RT Book, Section
A1 Long, Brit
A1 Koyfman, Alex
A2 Tintinalli, Judith E.
A2 Ma, O. John
A2 Yealy, Donald M.
A2 Meckler, Garth D.
A2 Stapczynski, J. Stephan
A2 Cline, David M.
A2 Thomas, Stephen H.
SR Print(0)
ID 1166812805
T1 Sickle Cell Disease and Hereditary Hemolytic Anemias
T2 Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260019933
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1166812805
RD 2024/04/23
AB Hereditary  anemias  result  from  defects  in  hemoglobin  production,  abnormalities  in  red  blood  cell  (RBC)  metabolism,  or  changes  within  RBC  membrane  structure.  Increased  hemolysis  occurs  because  the  RBCs  produced  are  either  abnormal  or  sustain  damage  after  release  from  the  bone  marrow  and  are  removed  from  the  circulation,  primarily  by  the  spleen.  Depending  on  the  compensatory  rate  of  production,  the  concentration  of  circulating  erythrocytes  may  decrease,  resulting  in  anemia.