RT Book, Section A1 Singh, Manpreet A1 Whitfield, Denise A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1181038452 T1 Afferent Pupillary Defect T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1181038452 RD 2024/04/24 AB Pupil size is controlled in the midbrain, from which efferent nerves travel to both pupils, resulting in symmetric pupils, even with a unilateral light stimulus. The perception of the light stimulus, however, may be decreased by disease within anterior visual structures such as the retina, optic nerve, chiasm, optic tract, and midbrain pathways. With diminished afferent stimulation, less light is “perceived,” and pupil contraction diminishes (ie, dilates) as a result. In this situation, the affected side is said to demonstrate an afferent pupillary defect (APD).