RT Book, Section
A1 Shah, Ashish
A1 Sobolewski, Brad
A1 Mittiga, Matthew R.
A2 Knoop, Kevin J.
A2 Stack, Lawrence B.
A2 Storrow, Alan B.
A2 Thurman, R. Jason
SR Print(0)
ID 1181044544
T1 Cat-Scratch Disease
T2 The Atlas of Emergency Medicine, 5e
YR 2021
FD 2021
PB McGraw-Hill
PP New York, NY
SN 9781260134940
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1181044544
RD 2024/04/24
AB Cat-scratch  disease  is  a  generally  benign,  self-limited  condition  caused  primarily  by  Bartonella  henselae  that  usually  manifests  with  regional  lymphadenopathy,  although  visceral  organ,  neurologic,  or  ocular  involvement  can  occur.  A  history  of  contact  with  saliva  or  scratch  from  a  cat  (especially  kittens  with  fleas)  is  usually  present.  Cat-scratch  disease  typically  starts  with  an  inoculation  lesion,  which  sequentially  will  appear  vesicular,  erythematous,  and  then  papular.  Lymphadenopathy  near  the  site  of  inoculation  usually  appears  within  2  weeks  of  skin  inoculation  and  may  persist  for  months.  In  rare  cases,  patients  may  develop  complications  such  as  ocular  disease  (neuroretinitis  and  Parinaud  oculoglandular  syndrome),  encephalitis,  osteolytic  lesions,  hepatosplenic  lesions,  weight  loss,  prolonged  fever,  and  fatigue.  The  differential  diagnosis  includes  lymphogranuloma  venereum,  bacterial  adenitis,  sarcoidosis,  infectious  mononucleosis,  tumors  (benign  or  malignant),  tuberculosis,  tularemia,  brucellosis,  and  histoplasmosis.