RT Book, Section A1 Hardin, J. Matthew A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1181043799 T1 Immune Thrombocytopenia T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1181043799 RD 2024/04/25 AB Immune thrombocytopenia (formerly idiopathic thrombocytopenic purpura [ITP]) occurs because of platelet injury and destruction. Pinpoint, red, nonblanching petechiae or nonpalpable purpura and ecchymoses are found on the skin and mucous membranes, either spontaneously (platelets < 10,000/mm3) or at the site of minimal trauma (platelets < 40,000/mm3). Petechiae are commonly found on dependent areas. Gingival bleeding, melena, hematochezia, menorrhagia, and severe intracranial hemorrhages may also occur. The newly diagnosed form affects children (peak incidence in 2- to 4-year-olds, equal gender distribution) after a viral illness or vaccination and completely resolves in 3 months. The chronic form occurs most often in adults, with women outnumbering men and a prolonged course of thrombocytopenia.