RT Book, Section
A1 Williams, Saralyn R.
A1 Thurman, R. Jason
A2 Knoop, Kevin J.
A2 Stack, Lawrence B.
A2 Storrow, Alan B.
A2 Thurman, R. Jason
SR Print(0)
ID 1181056686
T1 Levamisole-Induced Vasculitis
T2 The Atlas of Emergency Medicine, 5e
YR 2021
FD 2021
PB McGraw-Hill
PP New York, NY
SN 9781260134940
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1181056686
RD 2024/04/19
AB Levamisole  was  first  used  as  an  anthelminthic  for  human  and  veterinary  use.  Initial  human  use  in  the  1970s  for  inflammatory  conditions  resulted  in  publications  of  levamisole-associated  agranulocytosis  and  vasculitis.  In  2003,  the  US  Drug  Enforcement  Agency  identified  levamisole  as  an  adulterant  in  cocaine.  In  2009,  case  reports  of  agranulocytosis  and  vasculitis  associated  with  levamisole-contaminated  cocaine  were  published.  The  dermatologic  manifestations  may  include  retiform  purpura  with  possible  skin  necrosis  and  tend  to  appear  on  the  ears  and  nose  but  can  affect  any  area.