RT Book, Section
A1 Raffanti, Stephen P.
A1 Person, Anna K.
A2 Knoop, Kevin J.
A2 Stack, Lawrence B.
A2 Storrow, Alan B.
A2 Thurman, R. Jason
SR Print(0)
ID 1181057439
T1 Herpes Simplex Virus
T2 The Atlas of Emergency Medicine, 5e
YR 2021
FD 2021
PB McGraw-Hill
PP New York, NY
SN 9781260134940
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1181057439
RD 2023/03/23
AB Infection  with  herpes  simplex  virus  (HSV)  is  extremely  common  in  HIV-infected  patients  and  may  present  with  oral,  genital,  anal,  esophageal,  or  ophthalmologic  involvement.  The  hallmark  for  most  clinical  presentations  of  HSV  outbreaks  is  an  inflammatory  cutaneous  eruption,  with  or  without  vesicles,  and  pain.  HSV  esophagitis  is  seen  in  immunocompromised  HIV-infected  patients  and  presents  as  dysphagia  and  odynophagia  with  or  without  oral  lesions.  Idiopathic  aphthous  ulcerations  in  HIV-infected  patients  are  indistinguishable  from  HSV  lesions.  Perirectal  lesions  are  often  erythematous,  ulcerative,  and  extremely  tender,  with  a  predilection  for  the  gluteal  cleft.  Perirectal  HSV  may  also  be  associated  with  proctitis  and  anal  fissures.