RT Book, Section A1 Raffanti, Stephen P. A1 Person, Anna K. A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1181057478 T1 Thrombocytopenia T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1181057478 RD 2024/04/19 AB Thrombocytopenia occurs in 40% to 70% of all HIV patients. It can occur independently at all stages of HIV infection and may be encountered as the initial presentation of disease. HIV-associated anemia and granulocytopenia can occur concomitantly as the course of the HIV infection worsens, with thrombocytopenia seen in 30% of patients with CD4 counts less than 200/mm3. HIV patients with thrombocytopenia often present to the ED with bleeding (especially from the oral mucosa), ecchymosis, and petechiae. Secondary causes of thrombocytopenia are generally seen as the result of opportunistic infections, malignancy, or medications.