RT Book, Section A1 Stark, Christopher L. A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1186300057 T1 Herniation Syndromes T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1186300057 RD 2024/04/24 AB Severe head injury can result in extra-axial hematoma, cerebral contusion, or diffuse cerebral edema, which, in turn, may cause one of five brain herniation syndromes: uncal, central transtentorial, cerebellotonsillar, subfalcine, and external. Uncal herniation occurs when the uncus of the temporal lobe is displaced inferiorly through the medial edge of the tentorium. Compression of cranial nerve III can cause an ipsilateral dilated pupil. Typically, patients with uncal herniation are unconscious and require intubation. A contusion to the eye may also result in a dilated, nonresponsive pupil and arouse suspicion for uncal herniation, but typically these patients are alert.