RT Book, Section A1 Shah, Ashish A1 Sobolewski, Brad A1 Mittiga, Matthew R. A2 Knoop, Kevin J. A2 Stack, Lawrence B. A2 Storrow, Alan B. A2 Thurman, R. Jason SR Print(0) ID 1177127363 T1 Henoch-Schönlein Purpura (Iga Vasculitis) T2 The Atlas of Emergency Medicine, 5e YR 2021 FD 2021 PB McGraw-Hill PP New York, NY SN 9781260134940 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1177127363 RD 2021/01/17 AB Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis in children, with a peak incidence between ages 3 and 15 years and with 90% of patients younger than age 10. It is characterized by four main clinical manifestations. The classic exanthem of HSP begins with erythematous macules or urticaria that eventually coalesce and evolve into ecchymotic lesions and palpable purpura. The lesions are more often located on the buttocks and gravity-dependent areas (lower extremities) in ambulatory children. In nonambulatory children, the lesions can be seen on the face, trunk, and upper extremities as well. Mucosal involvement is rare; however, edema of the scalp, hands, scrotum, and periorbital tissue occurs.