RT Book, Section
A1 Hardin, J. Matthew
A2 Knoop, Kevin J.
A2 Stack, Lawrence B.
A2 Storrow, Alan B.
A2 Thurman, R. Jason
SR Print(0)
ID 1177132232
T1 Erythema Nodosum
T2 The Atlas of Emergency Medicine, 5e
YR 2021
FD 2021
PB McGraw-Hill
PP New York, NY
SN 9781260134940
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1177132232
RD 2021/05/09
AB Erythema  nodosum  (EN)  can  present  at  any  age  but  is  most  common  in  young,  adult  females.  Most  typical  is  bilateral,  erythematous,  subcutaneous,  tender  nodules  on  the  pretibial  and  lateral  lower  extremities  (usually  spares  the  posterior  calves).  Rarely,  the  nodules  can  be  found  on  the  thighs,  upper  extremities,  and  face.  Concomitant  symptoms  include  lower  extremity  edema  and  arthralgias.  Systemic  symptoms  can  include  fever,  headache,  and  gastrointestinal  complaints.  Generally,  the  nodules  resolve  over  days  to  weeks  with  flattening  and  a  change  in  color  to  a  blue-green  (like  a  deep  bruise).  There  is  no  ulceration,  and  the  skin  slowly  returns  to  normal.  Recurrence  occurs  in  up  to  one-third  of  cases.