RT Book, Section
A1 Cline, David M.
A2 Cline, David M.
A2 Ma, O. John
A2 Cydulka, Rita K.
A2 Meckler, Garth D.
A2 Handel, Daniel A.
A2 Thomas, Stephen H.
SR Print(0)
ID 56275380
T1 Chapter 95. Malaria
T2 Tintinalli's Emergency Medicine Manual, 7e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-178184-8
LK accessemergencymedicine.mhmedical.com/content.aspx?aid=56275380
RD 2022/08/18
AB Malaria  must  be  considered  in  any  person  who  has  traveled  to  the  tropics  and  presents  with  an  unexplained  febrile  illness.  Five  species  of  the  protozoan  Plasmodium  infect  humans:  P  falciparum,  P  vivax,  P  ovale,  P  malariae,  and  P  knowlesi.  The  organism  is  transmitted  by  the  anopheline  mosquito  bite  and  travels  hematogenously  first  to  the  liver,  where  asexual  reproduction  occurs  (exoerythrocytic  stage).  The  liver  cell  ruptures,  releasing  merozoites  that  invade  erythrocytes,  multiply,  and  cause  hemolysis  (erythrocytic  stage).  Malaria  also  may  be  transmitted  by  blood  transfusion  or  passed  transplacentally  from  mother  to  fetus.