RT Book, Section A1 Kefer, Michael P. A2 Cline, David M. A2 Ma, O. John A2 Cydulka, Rita K. A2 Meckler, Garth D. A2 Handel, Daniel A. A2 Thomas, Stephen H. SR Print(0) ID 56277940 T1 Chapter 132. Adrenal Insufficiency and Adrenal Crisis T2 Tintinalli's Emergency Medicine Manual, 7e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-178184-8 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=56277940 RD 2024/04/19 AB Adrenal insufficiency results when the physiologic demand for glucocorticoids and mineralocorticoids exceeds the supply from the adrenal cortex. The pituitary secretes adrenocorticotropin hormone (ACTH) and associated melanocyte stimulating hormone (MSH). ACTH stimulates the adrenal cortex to secrete cortisol. Cortisol has negative feedback on the pituitary to inhibit secretion of ACTH and MSH.