RT Book, Section A1 Hoffman, Robert J. A1 Punja, Mohan A2 Farcy, David A. A2 Chiu, William C. A2 Flaxman, Alex A2 Marshall, John P. SR Print(0) ID 55814729 T1 Chapter 40. Approach to Poisoning T2 Critical Care Emergency Medicine YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-162824-2 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=55814729 RD 2024/04/18 AB Patients with poison exposure and toxicity may present with a spectrum of various clinical signs, symptoms, and problems. Most of these are very straightforward and easily anticipated, but others may be unpredictable or associated with exposure to unidentified substances that hinder the clinician from knowing what to expect. There are, however, general principles that may be employed as a framework on which approach to most poisonings may be based. These are employed when managing adverse effects from poisoning by known or unidentified substances. Less than 5% of poisonings require use of specific antidotes; thorough general supportive care is the most important approach in caring for most poisoned patients.1