RT Book, Section A1 Nelson, Michael E. A2 Sherman, Scott C. A2 Weber, Joseph M. A2 Schindlbeck, Michael A. A2 Rahul G., Patwari SR Print(0) ID 1101225955 T1 Digoxin T2 Clinical Emergency Medicine YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-179460-2 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1101225955 RD 2024/11/11 AB Attempt to distinguish between acute versus chronic ingestions, as the symptoms and treatments differ.Electrocardiogram changes are common and include downward-sloping (scooped) ST-segment depressions, premature ventricular complexes, supraventricular dysrhythmias with slow ventricular rates, and bidirectional ventricular tachycardia.Although hyperkalemia can be a marker of significant digoxin poisoning, standard treatment with intravenous calcium should typically be avoided.Empirically administer digoxin-specific antibodies (5 vials for chronic toxicity, 10–20 vials for acute ingestions) to all patients with life-threatening dysrhythmias or hemodynamic instability.