RT Book, Section A1 Rosenbaum, David H. A2 Sherman, Scott C. A2 Weber, Joseph M. A2 Schindlbeck, Michael A. A2 Rahul G., Patwari SR Print(0) ID 1101224509 T1 Chronic Obstructive Pulmonary Disease T2 Clinical Emergency Medicine YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-179460-2 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1101224509 RD 2024/04/19 AB Respiratory infections are responsible for most acute exacerbations of chronic obstructive pulmonary disease (COPD).Beta-adrenergic agonists and anticholinergic drugs remain the primary bronchodilators and are most effective when used together.Steroids should be given to nearly all patients presenting to the emergency department (ED) with COPD exacerbations, and ongoing therapy should be prescribed for those patients who are discharged.Antibiotics are an important adjunct to therapy, although their use should be guided by the patient's signs and symptoms.Noninvasive ventilation is a critical component of therapy that is best used early in the ED course to avoid the need for intubation.