RT Book, Section A1 Kelly, Elizabeth W. A1 Fitch, Michael T. A2 Sherman, Scott C. A2 Weber, Joseph M. A2 Schindlbeck, Michael A. A2 Rahul G., Patwari SR Print(0) ID 1101225002 T1 Meningitis and Encephalitis T2 Clinical Emergency Medicine YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-179460-2 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1101225002 RD 2024/04/18 AB The classic triad of meningitis includes fever, neck stiffness, and altered mental status. However, all 3 of these are present less than half of patients with bacterial meningitis.Patients who are very young, very old, or immunocompromised may present with atypical signs and symptoms.Empiric antibiotics should not be delayed while waiting for a computed tomography (CT) scan before a lumbar puncture (LP) if meningitis is a likely diagnosis. When a CT scan is necessary, draw blood cultures and administer steroids and appropriate antibiotics before the LP.Consider the diagnosis of herpes simplex virus encephalitis in patients with focal neurologic findings or altered mental status and add intravenous acyclovir to the empiric antimicrobial regimen.