RT Book, Section A1 Howland, Mary Ann A2 Hoffman, Robert S. A2 Howland, Mary Ann A2 Lewin, Neal A. A2 Nelson, Lewis S. A2 Goldfrank, Lewis R. SR Print(0) ID 1108423074 T1 Antidotes in Depth T2 Goldfrank's Toxicologic Emergencies, 10e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071801843 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1108423074 RD 2024/04/20 AB Silibinin is the active ingredient in milk thistle, Silybum marianum, purported to prevent and treat amatoxin induced liver failure. Legalon SIL is a purified silibinin derivative available via an FDA approved open treatment as an investigational new drug (IND) for IV administration in patients suspected of ingesting amatoxin containing mushrooms.