RT Book, Section A1 Strecker-McGraw, Margaret A1 McGee, Khylie A1 Taylor, Ian A2 Stone, C. Keith A2 Humphries, Roger L. A2 Drigalla, Dorian A2 Stephan, Maria SR Print(0) ID 1106026639 T1 Thermal Injury & Smoke Inhalation T2 CURRENT Diagnosis & Treatment: Pediatric Emergency Medicine YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071799454 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1106026639 RD 2024/10/09 AB Burn injury results from exposure to heat, chemical, or electricity. The extent of the injury is dependent upon temperature and duration of exposure, as well as the vascular supply and the thickness of the injured skin. At the center of the exposure there is an irreversible tissue necrosis. Surrounding the area of central necrosis is a zone of ischemia in which there is a reduction in dermal microcirculation. This ischemic zone may progress to full necrosis unless the ischemia is reversed. At the periphery of the burn is a third zone of hyperemia characterized by a reversible increase in blood flow.