RT Book, Section A1 Sivilotti, Marco L. A. A2 Schafermeyer, Robert A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. SR Print(0) ID 1105686398 T1 Acetaminophen T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 4e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-182926-7 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1105686398 RD 2024/04/19 AB Widely available in both prescription and OTC products, acetaminophen is a common pediatric overdose.Acetylcysteine is the antidote for acetaminophen overdose and can be given orally or intravenously.Treatment with acetylcysteine is rarely indicated in children less than 6 years of age.Acetylcysteine is nearly 100% effective when started within 8 hours of acetaminophen ingestion.A child less than 6 years can be safely discharged following an acetaminophen exposure if the maximum ingested dose is less than 200 mg/kg or if acetaminophen is not detected in the serum at any time at least 1 hour after ingestion.