RT Book, Section A1 Lowry, Jennifer A. A2 Schafermeyer, Robert A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. SR Print(0) ID 1105686448 T1 Nonsteroidal Anti-inflammatory Drugs T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 4e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-182926-7 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1105686448 RD 2024/03/29 AB Nonsteroidal anti-inflammatory drugs (NSAIDs) are relatively devoid of toxicity in the overdose setting.Patients who develop toxicity exhibit central nervous system or gastrointestinal (GI) toxicity.Overdose of NSAIDs has been associated with an anion-gap acidosis.Long-term use of NSAIDs is associated with nephrotoxicity, including acute tubular necrosis, acute interstitial nephritis, and acute renal failure.