RT Book, Section A1 Juurlink, David A2 Schafermeyer, Robert A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. SR Print(0) ID 1105687058 T1 Carbon Monoxide, Cyanide, and Smoke Inhalation T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 4e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-182926-7 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1105687058 RD 2024/03/28 AB Smoke inhalation victims may have concomitant carbon monoxide and cyanide poisoning.Clinical signs and symptoms of carbon monoxide poisoning are notoriously nonspecific and correlate poorly with carboxyhemoglobin values.Carbon monoxide poisoning should be considered for an illness affecting more than one member of a family or group from a common environment.Cyanide poisoning is marked by rapid onset of central nervous system and cardiovascular dysfunction.Key laboratory features of cyanide poisoning include marked acidemia, striking lactate elevation, and a diminished arterial–venous O2 difference.Hydroxycobalamin is the antidote of choice for cyanide poisoning and early administration may be life saving.