RT Book, Section A1 Gussow, Leon A2 Schafermeyer, Robert A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. SR Print(0) ID 1105687222 T1 Organophosphates and Carbamates T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 4e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-182926-7 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1105687222 RD 2024/10/11 AB Organophosphate and carbamate insecticides inactivate the enzyme acetylcholinesterase resulting in a cholinergic crisis with the immediate threat to life being respiratory failure.The diagnosis is clinical with the history of exposure being key; the combination of miosis and increased salivation is relatively specific.Immediate administration of very large doses of atropine is life saving.Pralidoxime is an adjunctive antidote for organophosphate but not for carbamate poisoning.